[Analysis on clinical characters of pharyngeal paraesthesia in patients with different degrees of anxiety].

Objective:To investigate the therapeutic effect and potential reason for anxiety in pharyngeal paraesthesia in patients with different degrees of anxiety based on their characteristics.Method:All patients were divided into three groups according to self-rating anxiety scale(SAS)，including group 1（mild anxiety），group 2（moderate anxiety）and group 3（severe anxiety）.The characteristics,risk factors and prognosis in each group were compared and analyzed．Meanwhile，State-Trait Anxiety Inventory(STAI)was used to analyze anxiety state of all patients and healthy participates(Group 4)．SPSS13.0 statistical software was used for data analysis. Result:The proportions of female patients(54.05%) who had anxiety symptom were higher than those of male patients(45.95%).The proportions of moderate anxiety in female patients were higher(P<0.01),but those of mild anxiety were lower(P<0.01) compared with male patients. There was no gender difference about the proportions of severe anxiety. The patients aged 40-59 years had the highest proportions of anxiety(60.14%)and a higher proportions of moderate and severe anxiety compared with the patients aged 18~39 years and over 60 years old(P<0.05).However, there was no significant difference in proportions of different degrees of anxiety between the patients aged 18-39 years and over 60 years old(P>0.05).The proportions of mild anxiety in patients with 5-10 years duration and those of moderate anxiety in patients with the course of less than 5 years were all the highest.However, no difference was found in proportions of severe anxiety among different courses(P>0.05).The proportions of moderate anxiety(except mild and severe anxiety) in patients with no fixed occupation and no senior middle school education were higher than those in patients with fixed occupation and senior middle school education or above(P<0.05).But there were no relationships between the degrees of anxiety and other general conditions of patients,including marital status and live condition. Among different degrees of anxiety,the proportions of patients who feared cancer were all the highest, followed by stress and mental stimulation factors.The proportions of patients who feared cancer and felt stress were higher in severe anxiety than those in mild and moderate anxiety.But there was no significant difference between any two groups in other related factors,including mental stimulation factors, obsessive-compulsive disorder(OCD) and family history of psychosis.Male and female patients with different degrees of anxiety compared with healthy controls respectively,had significant difference in state anxiety(SAI) scores(P<0.05),but showed no significant difference in trait anxiety(T-AI) scores(P>0.05). Both recovery rates and total effective rates of mild and moderate anxiety were higher than those of severe anxiety(P<0.01).However,there was no difference between mild and moderate anxiety whether in recovery rates or in total effective rates (P>0.05). Conclusion:Pharyngeal paraesthesia in patients with different degrees of anxiety has different clinical features and prognosis .The main cause of anxiety appears to be a long duration of treatment. No obvious anxiety potential was found in patients compared with normal people.

[Influence of anti anxiety and anti depression treatment on sudden hearing loss].

Objective:To study the influence of anti-anxiety and antidepression treatment on patients diagnosed as sudden hearing loss with anxiety and depression symptoms.Method:A prospective and controlled study was carried out. A total number of 248 patients with anxiety and depression symptoms were randomly divided into experimental group or control group by Stochastic tables law. A number of 126 patients in experimental group accepted anti anxiety and anti depression treatment, while 122 patients in control group did not accepted anti anxiety and anti depression treatment. The hearing and tinnitus effects were evaluated.SPSS 13.0 statistical software was used for data processing.Result:According to the results of pure-tone threshold audiometry, in the 126 cases of experimental group, 48 were cured (38.1%), 25 were markedly improved (19.8%), 23 were effective (18.3%), and 30 were invalid (23.8%).The total effective rate was 76.2% (96/126). In the 122 cases of control group, 34 were cured (27.9%),17 were markedly improved (13.9%),18 were effective (14.8%),and 53 were invalid (43.4%).The total effective rate was 56.6%(69/122).The two groups had no significant difference in recovery rates but it showed significant difference in total effective rates. Moreover, the total effective rate of the flat type of sudden hearing loss in experimental group was superior to that in control group, however there was no significant difference in total effective rates of other three types between two groups. The patients who had concomitant symptom of tinnitus in experimental group and control group accounted for 85.7% (108/126) and 84.4%(103/122), respectively. However, no significant difference was found in proportions of patients with tinnitus between the two groups. According to the tinnitus results, in the 108 cases of experimental group, 32 were cured (29.6%),19 were markedly improved (17.6%), 36 were effective (33.3%), and 21 were invalid (19.4%). The total effective rate was 80.6%(87/108). In the 103 cases of control group, 19 were cured (18.4%), 15 were markedly improved (14.6%),22 were effective(21.4%),and 47 were invalid (45.6%).The total effective rate was 54.4% (56/103).The two groups had no significant difference in recovery rates but it showed significant difference in total effective rates. There was no significant difference in total effective rate of the low-middle frequency sudden hearing loss between two groups, but the total effective rates of other three types in experimental group were all higher than those in control group.Conclusion:The total effective rates of hearing and tinnitus can be improved after combination treatment with anti-anxiety and anti-depression in sudden hearing loss patients with anxiety and depression symptoms. Moreover, different types of the hearing curves of sudden deafness have different improvement degrees.